Department of Chemical Biology
Yang's Lab,Department of Chemical Biology, Xiamen University
Professor Yang
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Professor
Department of Chemical Biology, Xiamen University
Contact Information
Yang's LaboratoryRoom 532, Lujiaxi Building, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
Ph: +86 (0) 592-218 7601cyyang@xmu.edu.cn
Handheld Device for POCT work was Accepted by Angew Chem Int Ed.
2015-08-30 10:48:00
Zhu, Z; Guan,Z; Liu, D; Jia, S; Li, J; Lei, Z; Lin, S; Ji, T; Tian, Z; Yang, C* Translating Molecular Recognition into Pressure Signal for Rapid, Sensitive, and Portable Biomedical Analysis Angew Chem Int Ed 2015 DOI: 10.1002/anie.201503963
We demonstrate that a very familiar, yet underutilized, physical parameter—gas pressure—can serve as signal readout for highly sensitive bioanalysis. Integration of a catalyzed gas generation reaction with a molecular recognition component leads to significant pressure changes, which can be measured with high sensitivity using a low-cost and portable pressure meter.