Department of Chemical Biology
Yang's Lab,Department of Chemical Biology, Xiamen University
Professor Yang
Know more>>
Professor
Department of Chemical Biology, Xiamen University
Contact Information
Yang's LaboratoryRoom 532, Lujiaxi Building, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
Ph: +86 (0) 592-218 7601cyyang@xmu.edu.cn
Evolution of DNA Aptamers Work was Accepted by Biosensors and Bioelectronics
2016-01-18 10:17:39
There still lacks of specific and efficient methodology for early diagnosis and therapy of Gliosarcoma.We identified aptamers with high affinity specifically target gliosarcoma cell using whole cell SELEX technology. Truncated aptamer WQY-9-B, can not only recognize gliosarcoma cell from normal brain astrocyte but also clinical gliosarcoma tissue. Aptamer WQY-9-B can be internalized into gliosarcoma cell at 37℃which would be beneficial for potential target drug delivery and therapy.
