Department of Chemical Biology
Yang's Lab,Department of Chemical Biology, Xiamen University
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  • 159. Di Huang, Bingqian Lin, Yanling Song, Zhichao Guan, Jie Cheng, Zhi Zhu, and Chaoyong James Yang. Staining Traditional Colloidal Gold Test Strips with Pt Nanoshell Enables Quantitative Point-of-Care Testing with Simple and Portable Pressure Meter Readout. ACS Appl. Mater. Interfaces, DOI: 10.1021/acsami.8b15562

  • 158. Yanling Song, Yuanzhi Shi, Mengjiao Huang, Wei Wang, Yang Wang, Jie Cheng, Zhichao Lei, Zhi Zhu, and Chaoyong Yang   Bioinspired Engineering of Multivalent Aptamer-Functionalized Nanointerface to Enhance Capture and Release of Circulating Tumor Cells. Angew. Chem. Int. Ed. DOI: 10.1002/anie.201809337


  • 157. Jingjing Guo, Mingxuan Gao, Yanling Song, Li Lin, Kaifeng Zhao, Tian Tian, Dan Liu, Zhi Zhu, Chaoyong James Yang An allosteric-probe for detection of alkaline phosphatase activity and its application in immunoassay.  Frontiers in Chemistry DOI:10.3389/fchem.2018.00618

  • 156. Yanling Song1, Bingqian Lin2, Tian Tian2, Xing Xu2, Wei Wang1,Qingyu Ruan2, Jingjing Guo2, Zhi Zhu2, Chaoyong Yang1,2* Recent Progress in Microfluidics-based Biosensing. Analytical Chemistry DOI: 10.1021/acs.analchem.8b05007
  • 155. Wei Wang1#, Yingyan Wang2#, Liyuan Lin1, Yanling Song1, Chaoyong James Yang1,3* A Tridecaptin-Based Fluorescent Probe for Differential Staining of Gram-negative Bacteria. Analytical and Bioanalytical Chemistry

  • 154. Fenxiang Zou†a, Qingyu Ruan†a, Xiaoye Lina, Mingxia Zhanga, Yanling Songb, Leiji Zhoua, Zhi Zhua, Shuichao Lina, Wei Wangb, Chaoyong James Yanga,b Rapid, Real-Time Chemiluminescent Detection of DNA Mutation Based on Digital Microfluidics and Pyrosequencing. Biosensors and Bioelectronics 2019, 126, 551-557


  • 153. Huimin Zhang, Yuanyuan Yang, Xingrui Li, Yuanzhi Shi, Bin Hu, An Yuan, Zhi Zhu, Guolin Hong, and Chaoyong James Yang* Frequency-Enhanced Transferrin Receptor Antibody-Labelled Microfluidic Chip (FETAL-Chip) Enables Efficient Enrichment of Circulating Nucleated Red Blood Cells for Non-invasive Prenatal Diagnosis. Lab Chip , 2018, 18, 2749–2756

  • 152.Yanli Ma, Zhehao Lv, Tingyu Li, Tian Tian, Lianyu Lu, Wenli Liu, Zhi Zhu,Chaoyong Yang* Design and Synthesis of ortho-Phthalaldehyde Phosphoramidite for Single-step, Rapid, Efficient and Chemoseletive Coupling of DNA with Proteins under Physiological Conditions. Chem. Commun.2018, 54, 9434-9437



  • 151. Yahong Chen, Guoliang Ke,*‡ Yanli Ma, Zhi Zhu, Minghui Liu, Yan Liu, Hao Yan*‖ and Chaoyong James Yang*†§. A Synthetic Light-Driven Substrate Channeling System for Precise Regulation of EnzymeCascade Activity Based on DNA Origami. J.Am.Chem.Soc. 2018, 140 (28), pp 8990–8996

  • 150. Tian Tian , Yunpeng Bi , Xing Xu , Zhi Zhu and Chaoyong Yang* Integrated paper-based microfluidic devices for point-of-care testing. Anal. Methods 2018, 10, 3567-3581


  • 149. Wu, Q.; Wang, Y.; Wang, H.; Wu, L.; Zhang, H.; Song, Y.; Zhu, Z.; Kang, D.*; Yang, C.*. DNA aptamers from whole-cell SELEX as new diagnostic agents against glioblastoma multiforme cells. Analyst, 2018,143, 2267-2275

  • 148. Shi, L; Lei, J; Zhang, B; Li, B; Yang, C; Jin Y, Ultrasensitive and Facile Detection of MicroRNA via a Portable Pressure Meter.  ACS Appl Mater Interfaces. 2018, 10, 12526-12533



  • 147. Li, J.; Liu, F.; Zhu, Z.; Liu, D.; Chen, X.; Song, Y.; Zhou, L.; Yang, C.*. In Situ Pt Staining Method for Simple, Stable, and Sensitive Pressure-Based Bioassays. ACS Appl. Mater. Interfaces, 2018, 10, 13390–13396.

  • 146. Wang, Y.; Ruan, Q.; Lei, Z.; Lin, S.; Zhu, Z.;Zhou, L.;Yang, C.*. Highly Sensitive and Automated SERS-based Immunoassay for H5N1 Detection with Digital Microfluidics.  Anal. Chem. 2018, 90, 5244-5231.

  • 145. Lin, B.; Guan, Z.; Song, Y.; Song, E.; Lu, Z.; Liu, D.; An, Y.; Zhu, Z.; Zhou, L.; Yang, C.*. Lateral Flow Assay with Pressure Meter Readout for Rapid Point-of-care Detection of Disease-associated Protein. Lab Chip, 2018, 18, 965-970.

  • 144. Liu, D.; Tian, T.; Chen, X.; Lei, Z.; Song, Y.; Shi, Y.; Ji, T.; Zhu, Z.; Yang, L*;Yang, C.*. Gas-generation Reaction for Point-of-Care Testing. Analyst, 2018, 143, 1294-1304 .

  • 143. Ma, Y.; Mao, Y.; An, Y.; Tian, T.; Zhang, H.; Yan, J.; Zhu, Z.; Yang, C.. Target-Responsive DNA Hydrogel for Non-enzymatic and Visual Detection of Glucose. Analyst, 2018, DOI: 10.1039/C8AN00010G.

  • 142. Li, X.; Zhang, D.; Zhang, H.; Guan, Z.; Song, Y.; Liu, R.; Zhu, Z.; Yang, C.. A Microwell Array Method for Rapid Generation of Uniform Agarose Droplets and Beads for Single Molecule Analysis. Anal. Chem., 2018, 90 , 2570–2577.

  • 141. Tan, Y; Liu, W; Zhu, Z*; Lang, L; Wang, J; Huang, M; Zhang, M; Yang, C*, Selection and identification of transferrin receptor-specific peptides as recognition probes for cancer cells. Anal Bioanal Chem, 2018, 410, 1071-1077