Department of Chemical Biology
Yang's Lab,Department of Chemical Biology, Xiamen University
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Professor Yang

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Yang's Laboratory

Room 532, Lujiaxi Building, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China

Ph: +86 (0) 592-218 7601

Review Article by Huimin Zhang accepted by SCIENTIA SINICA Chimica

2019-05-07 17:03:00
Accurate cancer theranostics is important to improve the survival rate and life quality. Circulating tumor cell (CTC) is a type of tumor cells that spread through peripheral blood after detaching from a solid tumor, wihich is the most promising target in liquid biopsy. It offers non-invasive sampling for cancer diagnosis and real-time monitor of biological tumor information to study the mechism of tumor metastasis. However, the extreme rare and heterogeneity of CTC pose a huge technical challenge for CTC profiling. Various technologies have been proposed. This review aims to provide in-depth insights into CTC related research works from Yang’s group, including CTC targeting molecule discovery, microfluidic-based enrichment and high-throughput single cell analysis.