86-15859257624; zhanghuimin2017@foxmail.com
Work Experience ____________________________________________________
Jul 2020-Present Associate professor, Tan Kah Kee Innovation Laboratory, Xiamen University, Xiamen, China
Jul 2018-Jun 2020 Postdoctoral fellow, Institute of Molecular Medicine, Shanghai Jiao Tong University, Shanghai, China
Education ___________________________________________________________
Sep 2012-Jun 2018 Ph.D., Department of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China
Aug 2014-Dec 2015 Visiting Fellow, NIBIB, National Institutes of Health
Sep 2008-Jun 2012 B. S., College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, China
Honors and Awards _________________________________________________
2019 Second-class outstanding award of The 8
th China Innovation and Entrepreneurship Competition
2019 Postdoctoral Incentive Program of Shanghai Jiao Tong University School of Medicine
2015 Xiamen Airline Scholarship of Xiamen University
2015, 2016 Merit Student Award of Xiamen University
Publications ________________________________________________________
1.
Zhang, H#; Yang, Y
#; Liu, Y; Wang, Y; Ruan, W; Song, J; Yu, X; Wu, L; Zhu, Z; Hong, G*; Yang, C*; Stimuli-Responsive Microfluidic Interface Enables Highly Efficient Capture and Release of Circulating Fetal Cells for Non-Invasive Prenatal Testing,
Anal Chem, 2020, 92, 13
, 9281-9286.
2. Liu, Y;
Zhang, H*; Du, Y; Zhu Z; Zhang, M; Lv, Z; Wu, L; Yang, Y; Li, A; Yang, L; Song, Y; Wang, S*; Yang, C*, Highly sensitive minimal residual disease detection by biomimetic multivalent aptamer nanoclimber functionalized microfluidic chip.
Small, 2020, 2000949.
3.
Zhang, H; Wu, L; Lin, B; Wang, Y; Bi, Y; Wang, W; Song, Y;Yang, C*, Recent progress on microfluidic technology-based circulating tumor cell analysis.
SCIENTIA SINICA Chimica, 2019, 1220-1236.
4.
Zhang, H;Yang, Y; Li, X; Shi, Y; Hu, B; An, Y; Zhu, Z; Hong, G; Yang, C*, Frequency-enhanced transferrin receptor antibody-labelled microfluidic chip (FETAL-Chip) enables efficient enrichment of circulating nucleated red blood cells for non-invasive prenatal diagnosis.
Lab Chip, 2018,18, 2749-2756
5.
Zhang, H; Zhou, L; Zhu, Z; Yang, C*. Recent Progress in Aptamer-Based Functional Probes for Bioanalysis and Biomedicine.
Chemistry - A European Journal. 2016, 22(29):9886-9900
6.
Zhang, H;Ma, Y; Xie, Y; An, Y; Huang, Y; Zhu, Z; Yang, C*, A controllable aptamer-based self-assembled DNA dendrimer for high affinity targeting, bioimaging and drug delivery.
Sci Rep. 2015, 5:10099 (
cited by 65)
7.
Zhang, H;Song, Y; Zou, Y; Ge, Y; Zhu Z* and Yang, C*. A diazirine-based photocrosslinking probe for facile and efficient aptamer-protein covalent conjugation.
Chem Commun. 2014, 50(38):4891-4894
8. Li, X; Zhang, D;
Zhang, H; Guan, Z; Song, Y; Liu, R; Zhu, Z and Yang, C*. A microwell array method for rapid generation of uniform agarose droplets and beads for single molecule analysis.
Anal. Chem., 2018, 90(4):2570-2577
9. Yang, X; Liu, Z;
Zhang, H; Li, Z; Munasinghe JP; Niu, G; Teng, G; Chen, X*. Preclinical evaluation of an 18F-trifluoroborate methionine derivative for glioma imaging.
Eur J Nucl Med Mol Imaging., 2018, 45(4):585-592
10. Liu, D; Jia, S;
Zhang, H; Ma, Y; Guan, Z; Li, J; Zhu, Z*; Ji, T; Yang, C*. Integrating target-responsive hydrogel with pressuremeter readout enables simple, sensitive, user-friendly, quantitative point-of-care testing.
ACS Appl. Mater. Interfaces, 2017, 9 (27), 22252–22258
11. Zhu, G;
Zhang, H; Jacobson, O; Wang, Z, Chen, H, Yang, X, Niu, G; Chen, X*. Combinatorial Screening of DNA Aptamers for Molecular Imaging of HER2 in Cancer.
Bioconjug Chem. 2017, 28(4):1068-1075
12. Lin, B; An, Y; Meng, L;
Zhang, H; Song, J; Zhu, Z; Liu, W; Song, Y; Yang, C*. Control of CRISPR-Cas9 with small molecule-activated allosteric aptamer regulating sgRNAs.
Chem. Commun., 2019, 55, 12223-12226.
13. Wu, L; Zhu, L; Huang, M; Song, J;
Zhang, H; Song, Y; Wang, W; Yang, C*. Aptamer-based microfluidics for isolation, release and analysis of circulating tumor cells.
Trends Anal. Chem., 2019, 117, 69-77.
14. Wu, L; Ding, H; Qu, X; Shi, X; Yang, J; Huang, M; Zhang, J;
Zhang, H; Song, J; Zhu, L; Song, Y*; Ma, Y*; Yang, C*. Fluidic Multivalent Membrane Nanointerface Enables Synergetic Enrichment of Circulating Tumor Cells with High Efficiency and Viability,
J. Am. Chem. Soc. 2020, 142, 4800-4806.