上海交通大学, 医学院-新华医院, 课题组PI

教育经历:

(1) 2013-09 至 2018-06, 北京师范大学, 生物信息, 博士

(2) 2009-09 至 2013-06, 兰州大学, 数学与应用数学, 学士

博士后工作经历:

(1) 2018-08 至 2020-08, 上海交通大学，医学院-仁济医院

科研与学术工作经历:

在过去的五年里，以第一或通讯作者身份发表了24篇学术论文，包括1篇Nat. Biotechnol.、3篇Nat. Commun.、2篇Proc. Natl. Acad. Sci. U. S. A等。

1.Jiao Cao#; Zhong Zheng#; Di Sun#; Xin Chen; Rui Cheng; Tianpeng Lv; Yu An; Junhua Zheng*; Jia Song*; Lingling Wu*; Chaoyong Yang*; Decoder-seq enhances mRNA capture efficiency in spatial RNA sequencing，Nature Biotechnology,  2024. https://doi.org/10.1038/s41587-023-02086-y

2.Xinrui Lin#; Yingwen Chen#; Li Lin#; Kun Yin; Rui Cheng; Xin Lin; Xiaoyu Wang; Ye Guo; Zhaorun Wu; Yingkun Zhang; Jin Li*; Chaoyong Yang*; Jia Song*; mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq, Proceedings of the National Academy of Sciences of the United States of America, 2023, 120(39), e2307722120.

3.Xiaoxu Guo#; Fanghe Lin#; Chuanyou Yi; Juan Song; Di Sun; Li Lin; Zhixing Zhong; Zhaorun Wu; Xiaoyu Wang; Yingkun Zhang; Jin Li; Huimin Zhang*; Feng Liu*; Chaoyong Yang*; Jia Song* ; Deep transfer learning enables lesion tracing of circulating tumor cells, Nature Communications, 2022, 13: 7687.

4.Shichao Lin#; Kun Yin#; Yingkun Zhang#; Fanghe Lin#; Xiaoyong Chen; Xi Zeng; Xiaoxu Guo; Huimin Zhang; Jia Song*; chaoyong Yang*; Well-TEMP-seq as a microwell-based strategy for massively parallel profiling of single-cell temporal RNA dynamics, Nature Communications, 2023, 14:1272.

5.Li Lin#; Yufeng Zhang#; Weizhou Qian#; Yao Liu; Yingkun Zhang; Fanghe Lin; Cenxi Liu; Guangxing Lu; Di Sun; Xiaoxu Guo; YanLing Song; Jia Song*; Chaoyong Yang*; Jin Li*; LINEAGE: Label-free identification of endogenous informative single-cell mitochondrial RNA mutation for lineage analysis, Proceedings of the National Academy of Sciences of the United States of America，2022, 119(5): e2119767119.

6.Jia Song#; Yao Liu#; Xuebing Zhang; Qiuyue Wu; Juan Gao; Wei Wang; Jin Li*; Yanling Song*; Chaoyong Yang* ; Entropy Subspace Separation-based Clustering for Noise Reduction (ENCORE) of scRNA-seq Data, Nucleic Acids Research, 2021, 49(3): e18.

7.Xing Xu#; Li Lin#; Jian Yang#; Weizhou Qian#; Rui Su; Xiaoxu Guo; Linfeng Cai; Zirun Zhao; Jia Song*; Chaoyong Yang*; Simultaneous Single-Cell Genome and Transcriptome Sequencing in Nanoliter Droplet with Digital Microfluidics Identifying Essential Driving Genes, Nano Today, 2022, 46: 101596.

8.Kun Yin#; Meijuan Zhao#; Li Lin#; Yingwen Chen; Shanqing Huang; Chun Zhu; Xuan Liang; Fanghe Lin; Haopai Wei; Huimin Zeng; Zhi Zhu; Jia Song*; Chaoyong Yang*; Well‐Paired‐Seq: A Size‐ Exclusion and Locally Quasi‐Static Hydrodynamic Microwell Chip for Single‐Cell RNA‐Seq, Small Methods, 2022, 6: 2200341.

9.Ziyang Lu#; Fanghe Lin#; Tao Li#; Jinhui Wang; Cenxi Liu; Guangxing Lu; Bin Li; MingPei Pan; Shaohua Fan; Junqiu Yue; He Huang; Jia Song*; Chao Gu*; Jin Li*; Identification of clinical and molecular features of recurrent serous borderline ovarian tumour, eClinicalMedicine, 2022, 46: 101377.

10.Di Sun; Miao Sun; Jialu Zhang; Xin Lin; Yinkun Zhang; Fanghe Lin; Peng Zhang; Chaoyong Yang; Jia Song*; Computational tools for aptamer identification and optimization, Trends in Analytical Chemistry, 2022, 157: 116767 .

11.Yingkun Zhang; Xinrui Lin; Zhixian Yao; Di Sun; Xin Lin; Xiaoyu Wang; Chaoyong Yang; Jia Song*; Deconvolution algorithms for inference of the cell-type composition of the spatial transcriptome, Computational and Structural Biotechnology Journal, 2023, 21: 176-184.

12.Jia Song; Yuan Zheng; Mengjiao Huang; Lingling Wu; Wei Wang; Zhi Zhu; Yanling Song; Chaoyong Yang ; A Sequential Multidimensional Analysis Algorithm for Aptamer Identification based on Structure Analysis and Machine Learning, Analytical Chemistry, 2020, 92: 3307-3314.

13.Qianqian Zhang; Xing Xu; Li Lin; Jian Yang; Xing Na; Xin Chen; Lingling Wu; Jia Song*; Chaoyong Yang ; Cilo-seq: highly sensitive cell-in-library-out single-cell transcriptome sequencing with digital microfluidics, Lab on a Chip, 2022, 22: 1971-1979.

14.Liyuan Lin#; Jia Song#; Jian Li; Xiaolei Zuo; Hong Wei; Chaoyong Yang; Wei Wang ; Imaging the in vivo Growth Patterns of Bacteria in Human Gut Microbiota, Gut Microbes, 2021, 13(1): e1960134.

15.Xing Xu#; Qianqian Zhang#; Jia Song#; Qingyu Ruan#; Weidong Ruan; Yujie Chen; Jian Yang; Xuebing Zhang; Yanling Song; Zhi Zhu; Chaoyong Yang*. A Highly Sensitive, Accurate, and Automated Single-Cell RNA Sequencing Platform with Digital Microfluidics, Analytical Chemistry, 2020, 92: 8599-8606.

16.Xi Zeng#; Xiaoxu Guo#; Shaowei Jiang#; Xiaoping Yang; Zhixing Zhong; Siyu Liu; Zhi Zhu*; Jia Song*; Chaoyong Yang*; Digital-scRRBS: a cost-effective, highly sensitive and automated single-cell methylome analysis platform via digital microfluidics. Analytical Chemistry, 2023, 95, 13313−13321

17.Xi Zeng#; Shaowei Jiang#; Zhixing Zhong#;  Xiaoping Yang;  Qiuyue Chen;  Jin Li*;  Zhi Zhu*;  Jia Song*;  Chaoyong Yang*;  DIRECT: Digital Microfluidics for Isolation-Free Shared Library Construction of Single-Cell DNA Methylome and Transcriptome. Small Methods, 2023, 2301075.